Yousef Zakharia Selected Research

1-methyltryptophan

1/2021	Phase II trial of the IDO pathway inhibitor indoximod plus pembrolizumab for the treatment of patients with advanced melanoma.
1/2018	Indoximod: An Immunometabolic Adjuvant That Empowers T Cell Activity in Cancer.

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Yousef Zakharia Research Topics

Disease

45	Neoplasms (Cancer) 03/2024 - 08/2014
23	Renal Cell Carcinoma (Grawitz Tumor) 02/2024 - 01/2015
21	Melanoma (Melanoma, Malignant) 05/2023 - 01/2017
20	Carcinoma (Carcinomatosis) 10/2023 - 12/2018
8	Neoplasm Metastasis (Metastasis) 10/2023 - 02/2018
6	Prostatic Neoplasms (Prostate Cancer) 04/2024 - 01/2020
5	Urinary Bladder Neoplasms (Bladder Cancer) 04/2023 - 01/2022
5	Disease Progression 07/2022 - 01/2019
4	Diarrhea 10/2023 - 06/2021
4	Fatigue 10/2023 - 10/2017
4	Autoimmune Diseases (Autoimmune Disease) 01/2023 - 10/2016
2	COVID-19 03/2024 - 02/2022
2	Hypertension (High Blood Pressure) 10/2023 - 01/2021
2	Nausea 10/2023 - 07/2014
2	Dyspnea (Shortness of Breath) 01/2023 - 01/2022
2	Anemia 01/2023 - 01/2022
2	Exanthema (Rash) 01/2023 - 10/2017
2	Hypoxia (Hypoxemia) 05/2022 - 12/2018
2	Urologic Neoplasms (Urological Cancer) 01/2022 - 01/2020
2	Brain Neoplasms (Brain Tumor) 12/2021 - 03/2021
2	Lung Neoplasms (Lung Cancer) 06/2021 - 10/2018
2	Breast Neoplasms (Breast Cancer) 05/2011 - 03/2011
1	Thrombosis (Thrombus) 03/2024
1	Bronchiolitis Obliterans Syndrome 05/2023
1	Nephritis 01/2023
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2023
1	Scleritis (Episcleritis) 01/2023
1	Virus Diseases (Viral Diseases) 02/2022
1	Cough 01/2022
1	Rheumatoid Arthritis 06/2021
1	Bites and Stings (Sting) 06/2021

Drug/Important Bio-Agent (IBA)

19	Immune Checkpoint InhibitorsIBA 05/2023 - 01/2017
13	pembrolizumabIBA 10/2023 - 10/2016
9	Biomarkers (Surrogate Marker)IBA 01/2023 - 02/2018
6	RNA (Ribonucleic Acid)IBA 02/2024 - 01/2021
6	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 12/2018
5	Axitinib (AG 013736)IBA 10/2023 - 01/2015
5	PlatinumIBA 10/2023 - 12/2018
5	IpilimumabIBA 01/2023 - 03/2017
5	SeleniumIBA 05/2022 - 02/2018
4	Tyrosine Kinase InhibitorsIBA 01/2023 - 01/2017
4	NivolumabIBA 01/2023 - 01/2017
4	EnzymesIBA 01/2022 - 01/2018
3	DNA (Deoxyribonucleic Acid)IBA 02/2024 - 01/2020
3	avelumabIBA 10/2023 - 01/2022
3	cyclopropapyrroloindoleIBA 10/2023 - 01/2020
3	erdafitinibIBA 04/2023 - 01/2019
3	VaccinesIBA 01/2023 - 01/2018
3	MicroRNAs (MicroRNA)IBA 05/2022 - 02/2018
3	CreatinineIBA 01/2022 - 10/2017
3	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2022 - 01/2019
3	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2021 - 01/2015
2	durvalumabIBA 02/2024 - 01/2023
2	Agammaglobulinaemia Tyrosine KinaseIBA 05/2023 - 10/2021
2	Formaldehyde (Formol)FDA Link 05/2023 - 01/2020
2	ParaffinIBA 05/2023 - 01/2020
2	Immunoconjugates (Immunoconjugate)IBA 01/2023 - 03/2022
2	cabozantinibIBA 12/2021 - 01/2019
2	Tryptophan (L-Tryptophan)FDA Link 10/2021 - 01/2018
2	Indoleamine-Pyrrole 2,3,-Dioxygenase (Indoleamine 2,3 Dioxygenase)IBA 10/2021 - 01/2021
2	InterferonsIBA 06/2021 - 12/2020
2	talimogene laherparepvecIBA 06/2021 - 01/2019
2	AndrogensIBA 01/2021 - 01/2020
2	1-methyltryptophanIBA 01/2021 - 01/2018
2	AlbuminsIBA 01/2021 - 10/2020
2	atezolizumabIBA 01/2021 - 12/2018
2	AntioxidantsIBA 05/2020 - 02/2018
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2019 - 01/2017
1	guadecitabineIBA 02/2024
1	ibrutinibIBA 05/2023
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 04/2023
1	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2023
1	Lipase (Acid Lipase)FDA Link 01/2023
1	Amylases FDA Link 01/2023
1	Sunitinib (Sutent)FDA Link 07/2022
1	Protein Isoforms (Isoforms)IBA 05/2022
1	enfortumab vedotinIBA 03/2022
1	GlutaminaseIBA 01/2022
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2022
1	MTOR InhibitorsIBA 01/2022
1	Everolimus FDA Link 01/2022
1	sapanisertibIBA 01/2022
1	Glutamine (L-Glutamine)FDA Link 01/2022
1	eribulin FDA Link 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 01/2022
1	Toll-Like Receptor 9IBA 12/2021
1	Chemokine CXCL10IBA 12/2021
1	Membrane Proteins (Integral Membrane Proteins)IBA 10/2021
1	Vinblastine (Vinblastine Sulfate)FDA Link 06/2021
1	AntibodiesIBA 06/2021
1	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2021
1	CalciumIBA 06/2021

Therapy/Procedure

47	Therapeutics 04/2024 - 08/2014
18	Immunotherapy 05/2023 - 08/2014
12	Drug Therapy (Chemotherapy) 10/2023 - 07/2014
4	Radiotherapy 01/2023 - 01/2018
2	Castration 04/2024 - 01/2020
2	Adjuvant Chemotherapy 01/2022 - 01/2019
1	Precision Medicine 04/2024
1	Adjuvant Radiotherapy 01/2023